The default output of BioSap is XML, thus, making the results very portable.
- The data will be used to generate input files for Lombardi
(Ink-Jet Microarray Synthesizer Control Software).
- The data will be shared among different labs by including information
that will allow it to interface with MIAME compliant databases
(http://www.mged.org/Annotations-wg/index.html).
- The results of the microarray experiments generated will be used to
optimize future experiments and facilitate discoveries.
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The data gathered from each run of the BioSap pipeline will be imported
into a local ISB database.
- The output of different formats of the data, including: FASTA, ASN.1,
XML, etc. will be accomplished through stored procedures in the database.
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The software is designed in a modular fashion to make further development
easier.
- Further development is anticipated in the areas of parameter and output
expansion.
- Further development is being considered for algorithm optimization to
improve the success rate (although current success rates can exceed 98%,
given good parameters).
- The software will be expanded to pick overlapping oligonucleotides that
can be annealed, ligated and cloned to produce kilobase-length DNA, a new
application of ISB's ink-jet oligo synthesizer.
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Blast Integrated Oligonucleotide Selection Accelerator Package